[effect of the Administration of the Thyroid Hormone on the Levels of Tsh and Lats in the Serum of the Thyroid Patients].

نویسنده

  • A SAKAGAMI
چکیده

緒 言 1916年Smithが マウスにおい て下垂体剔出時, その甲状腺が萎縮する事実 より下垂体には甲状腺 刺激作用のあること を推論 し,1929年 にはLoeb らがその作用物質,即 ち甲状腺刺激ホルモン(T sx)の 抽出に成功するに及び下垂体 と甲状腺の 有機的 な関連性が注目されるに至つた.更 にこの 後Aronら が下垂体のTSH分 泌 は 循環血中の甲 状腺ホルモン(以 下 「甲ホ」 と略)量 に よって調 節され るこ と,即 ち両者間にfeedback relation が存す ることを認めて以来,こ れが甲状腺機能調 節機構の主軸 をなすと考 えられる様 になつた. 各 種 甲状 腺 疾 宙、々 者 に お け るBMR,PBI, 或 い は1311摂 取 率 等 に よ る 機 能 検 査 は 日常routlne に 行 なわ れ て い る が,一 歩 進 め て 上 位 調 節 中 枢 と の 関 連 よ り甲 状 腺 機 能 を 把 握 す るfeedback re-

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عنوان ژورنال:
  • Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine

دوره 52  شماره 

صفحات  -

تاریخ انتشار 1964